Jon Tickle Reunites with Big Brother 4 Cast After MND Diagnosis
Jon Tickle joined former Big Brother housemates for a long-awaited reunion, as friends reflected on his MND diagnosis and fundraising ride.

More than two decades after Big Brother brought them together, Jon Tickle and his former housemates have reunited in London. The gathering carried a bittersweet note: Tickle, 52, was diagnosed with Motor Neurone Disease (MND) a few months ago, his co-star Ray Shah said.
Shah posted photographs from the dinner on Instagram, describing it as the first reunion for most of the group in 23 years. His caption recalled their time on the fourth series, calling the cast “one of the OG’s” and saying the London get-together brought plenty of laughter. He also credited Joanne Rooney, known on the programme as Sissy, with helping bring everyone together.
That reunion links a chapter of shared television history with a difficult present. Shah said the news of Tickle’s diagnosis brought “a touch of sadness” to the evening, while also looking ahead to another meet-up with the full group. The mix of affection and resolve in his message gives the gathering its weight: the old housemates have found each other again, and plan to keep doing so.
The fourth series aired in 2003, during the show’s original Channel 4 run. Its cast included Shah, Scott Turner, Steph Coldicott and eventual winner Cameron Stout, names that made the dinner a reunion of the group rather than a simple catch-up between two former contestants. The series’ line-up also featured Tickle, whose most unusual moment in the house came after his eviction: he won a chance to return, though he could no longer win the series.
That second stint helped make him one of the season’s memorable figures, but his public identity didn’t stop at reality television. A physics graduate with an evident interest in explaining science, Tickle later appeared on the Sky series Brainiac: Science Abuse. It was a very different platform from the house: the appeal was his ability to make scientific ideas entertaining for a broad audience.
MND affects nerve cells in the brain and spinal cord, progressively impairing the muscles used for movement, eating and breathing. There is no cure. Tickle made his diagnosis public in September, saying he had received it earlier that year. His account has since included a demanding fundraising effort that puts the condition’s physical effects into sharp focus.
In a video message, he explained that his voice reflected the disease and thanked supporters backing a cycling challenge for the MND Association. The route took him and fellow riders up the Col du Galibier in the French Alps. Tickle said his left leg was producing less than half its former power, making the climb a long one, but he intended to complete it.
Huge thanks to everyone who has sponsored the NOBSON Cycling Club's ride up the Col du Galibier later this week in aid of the MND Association. Here's how to make a donation if you haven't done so yet. Thank you!
— Jon Tickle (@TheJonTickle) September 22, 2026
Fundraising page: https://t.co/K4qCiEskXD pic.twitter.com/ih14mPPpZg
The ride was completed, and the team raised more than its £25,000 target. That result gives the challenge a concrete measure of its reach, while Tickle’s own description of the climb makes clear what it demanded from him. His decision to speak openly about his changing strength and voice also gave supporters a direct account of why the fundraising mattered.
Tickle has spoken before about the trade-offs that followed his television breakthrough. In a 2018 interview with The Guardian, he said his profile led to seven series co-presenting Brainiac. He also described balancing television work with a science career as difficult, saying a convenience-food diet during five years of that double life resulted in the removal of his gall bladder. He felt his career might have progressed further had he concentrated on it in his early thirties.
He recalled both the opportunities and the labels that came with fame: he was glad his profile opened doors, but wished colleagues would sometimes introduce him by his work as an enterprise information architect rather than by a television stunt involving custard. The contrast captures the unusual career he built after the show: science, entertainment and a lasting association with one of the programme’s most striking moments.
At the reunion, co-stars Justine Sellman and producer Kerry Allison also shared warm messages, with both expressing how good it was to see the group again and hoping they would meet sooner next time. For Tickle, the gathering and the completed climb point in the same direction: friends are making time together, while his fundraising effort keeps attention on MND and the people living with it.